Yes, but the less i tweak, the closer i'm supposed to be from the original amp. It's like with the XTC provided with the Kemper, It's far away of what i obtained and liked with the XTC and XTC classic i owned for years. The amp have many possibilitys and internal interaction. A single profil can't cover the full abilitys of one channel. I don't like to have too much gain, and if the profil was taken with a lot of gain, it probably have missed (a little) something if i want to use it with a moderate gain.
Just like an amp setted with a lot of gain, with the guitar volume turned down, you will not obtain the same result than with the amp setted mid gain, but guitar volume fully opened (even with a guitar that have a very linear spectrum respons to volume).
But make 10 profiles of one channel just with various settings of the gain is useless for sure, 2 or 3 profile is enough as the drive parameter of the Kemper is very efficient.