I haven't been playing the heavy stuff much lately so I thought I would give this one a shot. I recently downloaded the Lasse Lammert metal profiles for my Kemper and they are just awesome. I picked a profile called "Nineties First" with an explanation of the profile in his words:
Maxon OD820 > Mesa Rectifier Rackmount with Mercury Magnetics transformers
> Marshall 1960AV 4x12 cabinet with V30s > SM57
Very tight and articulate rhythm sound with not too much gain and an “open” harmonic structure.
Lead was recorded using another called "Liquid Leads":
Maxon OD808 > Soldano HotRod 100+ with SLO100 Specs
> Mesa Stiletto 4x12 cabinet with V30s > SM57 + R121
No matter what guitar, pickup or tuning, this will put a smile on your face and inspire you...
I also used a killer sounding bass profile for the clip too.
As you can see I used my Anderson Pro Am. I know I didn't play the tune (rhythm and lead) note for note but at least my vibrato is better than Kirk's.