Here are 4 presets of my mesa boogie amp, Orange and Red Modern channels.
The "Rythm" versions are slightly mid and gain scooped versions integrating a comp, a tube screamer/pure boost (depend on which you prefer), low and high cut EQ on the "MOD" section and a presence boost on the "X" section. The purpose was to give a mixing version of the amp directly for recordings.
The "Modern" versions are direct profiling without cabs, with all knobs set to noon (gain, bass, mid, trebble, presence). The purpose is to enjoy the real amp with your own settings, especially if you play with power amp + guitar cabs !
PS : Sounds calibrated for passive humbuckers