Difference between 2 and 3 is clear and it does sound like the cab has changed - I wonder if the change to the next profile preloads the cab of that profile (in code) and doesn't release it if you switch back to the first profile. What happens if you put the same profile next to itself and do the switch then? What happens if you put two profiles with the same cab next to each other and do the switching around then?
I'd test it myself but I'm not going to 1.04 until we have the issue ironed out and I don't have the problem.
Unfortunately it's not a cab change. I have the same problem when I switch between two rigs using the same cab. On start up Rig 1 (normal sound) then switch to Rig 2 (same cab as Rig 1) back to Rig 1 - sound changed - more scooped and more presence/fizziness and also slight increase of volume (about 1 db). For now my workaround is to engange a master eq where I cut a little bit of presence and increase midrange by about 0.5 - 1. Works ok until the fix.
Besides this ugly bug 1.06 seems to be really cool and stable I think. So, I hope they manage to fix that soon and then we are all rocking again.