Profiling a Marshall Studio Jubilee

Why not try it and see how it comes out? Do it, 90 seconds later, you'll know.

I checked the manual, not sure if I looked at the correct manual because there are a few variations of the model but it says "Note: the DI output has added loudspeaker emulation", so if that's the case then you won't get a true "Direct Amp Profile". It still might sound good so it's sure worth a try. Also, the Kemper can usually tell if a cab is or is not involved while profiling and it will tell you so it would be interesting to see what it says after the profiling process. I don't remember exactly what happens but I'm pretty sure if it doesn't detect a cab the resulting profile won't have a cab (the cab light will not be on) after the profiling process, someone please correct me if I'm wrong.

Also, the DI location does not include the power amp section.