Missing something....

You'll need to share your entire set up before anyone will be able to help you.

The search for "that" sound is always a challenge.

90% of the sound comes from the fingers anyway...but that's not helpful.

The only thing I can suggest is to look at the type of amps used for that sound and narrow your search. The guitar/pickups will play a big factor in that long sustain - not a typical strat sound so are they active or stacked humbuckers? Sustain is the key here without too much gain..

In general; use the Lead Booster but you don't have to necessarily crank the gain of the amp. You can also try using a Wah but leave it in one position for lead solos.

Quote from BayouTexan

Use the Lead Booster but you don't have to necessarily crank the gain of the amp. You can also try using a Wah but leave it in one position for lead solos.

Keep in mind that the Lead Booster will sound like a dramatic change in tone when playing alone. In the context of a band mix, it helps the guitar 'poke out' and doesn't sound nearly as different as you think.

In reality, a LOT of iconic guitar sounds are somewhat.....awful, when isolated. Some Brian May stuff sounds horrid by itself. Then in the mix it's like "OH......I see..."

Quote from Ruefus

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In reality, a LOT of iconic guitar sounds are somewhat.....awful, when isolated. Some Brian May stuff sounds horrid by itself. Then in the mix it's like "OH......I see..."

So true. I heard an iso track of Hendrix (I think it was Purple Haze track). It was totally awful. I actually thought is was someone else trying to sound like Hendrix. Since I started mixing, I come at this in an entirely new perspective. OP, can google some iso tracks and see what we mean.

He may be playing a Clapton Strat in that video. I saw what looked like lace sensor pick ups on it, and he may very well be using the mid boost built into the guitar, too. Even when the mid boost is not turned on, the guitar has a hot output from the active preamp.I think using that kind of guitar, you would be able to get that kind of a sound with Kemper factory rigs, like black face or tweed fenders, Or medium gain Marshall’s. Be sure and turn up your volume loud enough to get that kind of sustain interaction with your speakers.

Quote from paults

He may be playing a Clapton Strat in that video.

I'd bet money on that. You know Clapton is.

With this recorded in '90 the Clapton model was only 2 years old, and Torino red was an option. If he's backing up Clapton with a red Strat loaded with Lace Sensors and a 6-screw bridge? That's a Clapton model. Period.

It was a long time ago....but I believe the Clapton model was the only Strat with a 6 screw bridge and Lace Sensors at the time. The 2 point trem was on the higher-end models. Lace Sensors only came on the upscale stuff as well.

Also - pay close attention to where the pickup selector is. The tone isn't the nasally sound associated with the 2 and 4 positions.....but he's clearly using the 2 position. Clapton *gasp* is using the middle pickup alone. Rather uncommon.....but dang that sounds good.

I have an 80s American Standard that came stock with Lace Sensors. I added the Clapton circuit to it. I use the middle pickup all by itself a lot. It is a really useful sound with those pickups.

Quote from MichaelsCloud

Good point, thanks for the advice.

simple set up..

US Strat, Kemper stage, into headphones, or Yamaha HS5’s via scarlet 8i6 (sp/dif)

Like I mentioned earlier, you will have to play loud enough for your Yamaha speakers to be able to interact with the guitar pick ups to get that kind of singing sustain.

A good monitor will get you feedback too. The kemper kabinet works extremely well for that. You can try a digitech freqout but I don't find it as easy and natural as real natural feedback is to control.

Hehe a freqout is great, but not needed here. These sounds are really compressed though so use a healthy amount of gain.

I find the most important thing with a Strat is to roll back the tone a bit to remove the "ice pick" and turn up the amp. That gives a fatter sound.

The Clapton Strat has a 25db preamp booster in the circuit and a mid boost tone control (to get humbucker sounds according to him) so in reality he could be driving the amp input very hard. As others have said, a Lead Boost might be a good start or even a Kemper Drive to cop some of the mid boost that is possible from that guitar.

sounds like an amp that's wide open (volume, not gain, although there is certainly enough there, too).

IOW: Loud! Very loud.

As others have pointed out, controlled feedback.

And most likely the Clapton mid boost