Kemper Main outs Left and Right go to your UR22 Left and Right inputs... using TS cables.
Gains knobs on the interface should be at about number 3. (9 o'clock position).
"Powered" Speaker Monitors should have their volume knobs at about 85% not at MAX... and connected using TRS cables.
DAW volume track levels should be set at 0.0db on the meters.
What type of monitors are you using?