Actually I guess once an Amp (+ eventually cabinet, mics etc) is ready to be profiled, it's not a big effrort to change settings and grab another 'screenshot' out of it. it just takes 1 minute or 2.
I mean, Usually from each amp. I get a couple ot cleans, 2 or 3 crunch and one or two Lead Sounds, .. let's say 3 main settings and one alternative each. that's probably enought.
But If you don't know exactly what kind of sound You're looking for (or if You're not the only one who's gonna use those profiles) well it's easy to end with 12..15...20 profiles of the same amp.
Of course 125 Profiles seems a bit excessive, ..
About the Effects, .. well it's ok to find them already there: it can be usefull to undestand better what that profile it's supposed to be or just to discover different effect' settings You've never explored before.
If You don't like them, just turn them off or change them with Your favourite effect preset. it's not a big issue.