I disagree BT. think 'theplayer' is right in trying to cover both parts.
You could play it with intervals but not easy. Also, intervals with distortion wouldn't have the clarity that the KPA harmoniser on single notes would have I would think.
The audience will still like to hear the harmony, as on the original.
Anyway, the guitar parts arent the hard thing on that track.....THE VOCAL IS ! 
If that is the case you could do the outro with 4 profiles, each one set at the next harmony up along the scale but it would mean stepping on pedal 2,3 & 4 for the outro.
From what I remember, the main melody moves up as well with the hearmony a major 3rd above? Am I wrong ?
Hank has come up a few times in the Forum over the years.You should do a search and see what other users have chatted about .
Also,welcome to the Forum !!!
what guitar and lead profile?
I can hear Donald singing ! Lovely tune,sound and above all playing Mats
I remember getting some 3rd party early 70's Big Muffs that could be imported to work as pedals about 10 years ago....never saw any more of that since though
Welcome along ! ( bring lots of good profiles )
When you're around as long as me and Zappledan you learn to get a bit relaxed BT
I use a Shure in ear pack and always use monitor & direct as left/right
Excellent suggestion.
My preference would always be to view in #'s but thats just me.
Welcome along .....enjoy !!!
I use 'The Amp Factory' IIB profile for years as a crunch / lead sound.
I think I changed the CAB ( due to the usual ear fluctuations )on it a few times but it works great for me.
it is best to have both, one cannot replace the other.
the voicings used on each instrument make that obvious: on keys it's often an octave in the bass and the upper chord is structured in thirds (good luck fretting that on a guitar), while chords on a guitar (in standard tuning) rely mostly on fourths and fifths (the g-b pair of strings being the exception).
This is partially why piano played on guitar and guitar played on a keyboard will always sound off.
The interface influences the outcome quite audibly.
I guess it depends what you want the midi interface for though.If its for live work to replace a layered keyboard then that would be difficult but for single note stuff and simple one position chord work it should be fine.
JamOrigin is your best bet I think
