OhG It works as advertised. Clean sense and Distortion Sense are meant to be set per guitar. So, for example, I set Clean Sense for my Tele so that I get light orange flashes on the loudest strokes. If desired I, set Distortion Sense to a positive value to make up for the Teles lower Output compared to my BC Rich with a Seymour Duncan JB humbucker, to achieve a similar level of distortion on the same Rig.
In fact I do NOT compensate in order to have a Rig react like the profiled amp would do: I use the BC Rich and have a more saturated tone, I use the Tele with its lower output and get a lower gain. IF you‘d like to have your lower output guitars to achieve the same gain as your higher output guitars, increase DS and compare until you are in the same range.