I never looked at that setting, wonder why its on mono. I will change it and check things. Also I never had analog TRS plugged in at the same time as SPDIF so there wouldn't be any issues with that.
[edit] actually that doesnt have a stereo setting..
Also, your master stereo and your SPDIF are setup differntly from each other. One is master mono, the other is master stereo. Make sure that is rectified, you can't really compare the two results otherwise.