Personally, I'd rather just see some continued work on the current Kemper. Maybe:
Rig Manager improvements, many already talked about.
Easy to use UNDO/REDO
Incorporating Presets into the edit screens for various effects. For example having a drop down of all Distortion presets along with the few controls. I know you can find then in the treeview, but why not show just the presets you might while editing?
Save/Save As and Copy/Paste that are a bit more obvious like on the hardware.
Add the Stomp and Effect presets that already exist on the hardware. (many of us still use this)
Maybe there could be a way to assign multiple effects to each of the 8 buttons. This might be a way to extend without needing new hardware. It might require creative soft buttons to do things like turn on a distortion while leaving compression alone if both are on A, but it seems possible.
I'm sure there are lots of other possibilities.
On the Profiler
Everyone always says there can't be multiple profiles, but then how does Performance mode preload five of them for zero latency switching? Maybe this leaves a path to allow morphing between the rigs in a Performance. Still not really two amps at once, but the morph might be more useful to more people.
On running multiple rigs - maybe some kind of hardware add on to the current Kemper? Not really a second Kemper but a way to add in a second rig like an effect? Same way you might use the effect loops.
Extend locking to allow locking specific parameters instead of just groups. So rather than locking X, allow locking specific components of what is loaded in X.
Maybe a new Kemper alternate foot controller that works more like a standard Midi controller with enough buttons to manage all separate effects and Rig Manager editing with humanized control (easy assignments of CC or program change, etc.
So yes, there could be a new Kemper 2. But there also would seem to be many ways to keep on extending what we already have.