I’m constantly hearing digital amp enthusiasts say using the (insert digital amp brand here) your amp will be consistent every night. We’ll no duh, not changing your amp controls will give you the same sound every night. It’s the room that changes. Bing bong! That’s why you adjust the knobs. Thoughts? Masters and geniuses only please. The way music is going it is consistent every night. Know why? It’s pre recorded. So grab your digital amp and your prerecorded music and rock it I guess 🤷♂️ yup I’m old. Also guilty of doing both and loving guitar and playing music. Just pointing out the BS.
In my opinion you throw everything into one simple thing here. First of all, yes the room, the stage and also the amount of people in the room have a big impact to the overall sound. But this can't be compensated by just fiddeling some knobs standing next to your amp, that's pure guesswork because you don't have any clue about how this will translate to the audience.
Also with a conventional setup of amp, cabinet and microphone the impact of what you fine tune on your knobs compared to a different mic position is close to marginal for what people here out of a PA system.
So yes, being consistent can help a lot for a fast and reliable setup and sound, so the sound guy/girl can focus on matching your sound to the room and everything else, without having the guitarist on stage doing guesswork on the amp knobs.
Also if you're on tour with an own sound tech and setup you are lightning fast if the basic setup is the same. This doesn't mean that you can't achieve this with a classic setup, but take a look how this is done on tour, you find markers everywhere, where the knobs have to be, where the mic has to be positioned and as long as there is nothing completely going wrong you also don't touch your knobs.
All said for stage setups with a PA, if you play gigs where you have to do your front sound with the cabinet, that's kinda different story.