Ok Ive done a couple of profiles using this method.
The afd100nc and evh5150nc profiles I did were KPA>amp>palmer PDI03 (direct out)>KPA>atomic FRFR>5150 4x12
The profiles sound and feel pretty much spot on to what the amp does with the powersoak/reamp
I can see what the op is trying to achieve here, its exactly what I went for too.
Don't know if its something to do with the THD (I can't see what though).
The feel of the profile is very dependent on how the master volume is set if thats any help.
High master volume = smoother with less obvious dynamics.
Try out my profiles see what you think through power amp/guitar cab.