There were no profiling changes in 5.x, so nothing in 5.x could cause problems when Profiling.
Good to know. Maybe my issues I'm having were always there or pilot error (or both). I will say that the profiles I made yesterday were spot on. I always record the finished profile along with the miked amp simultaneously before moving on so as to a/b the two. It's been over a year since I've profiled and feel things have improved in terms of quality.