Those are the latest official versions (not including betas) so you're all good there.
I've had a few 'moments' with a Macbook Air where the USB port has shut down thus preventing any communication. Unplugging and replugging doesn't fix it. I think the mac is shutting down the port for some reason - i.e. not a Kemper issue (unless the Kemper is pulling too much current) - it is fixed by rebooting the mac.
I have read (elsewhere on this forum) the suggestion that you put the mac to sleep and then wake it up again to cure the problem but I am not entirely convinced. I did ask the Kemper team about this but they didn't have the same issue - maybe its a laptop as opposed to a desktop problem.
Seeing as you have already tried various rebooting sequences this of little use so I think I would be inclined to remove and re-install Rig Manager.
Then reload your backup file (you made one didn't you?!) and see what happens