Yeah, I always set the PS2 to flat no matter what. Sometimes it's tempting to "fix" a profile by adjusting the switches on the PS2, but it's better in the long run to simply abandon the profile if you can't dial it in on the Kemper. Save the PS2 controls for dialing in the room, for me that's a lot easier than using the global outputs. Don't forget that to achieve a flat response, the PS2 dials should be turned all the way to the left, NOT be at noon.
Imprints work on all profiles. People get way to preoccupied with studio/direct/merged. There is no rule on what sounds best, trust your ears. I also want to point out that as much as I am enjoying the Kones, I haven't sold off my real speakers yet. CK is so so so close, but when it's just me in a room, real speakers are much sweeter