I just had to roll back to the release OS and restore my back up. After about an hour of playing around and practicing, things got funky sounding, it sounded almost like a combination of fret buzz and a dirty volume pot crackle (sorry I didn't record it). I rebooted and tried changing modes and other rigs, no change, still bad sounding. I tried 2 different guitars and cables just to make sure.
I restored my back up first with the beta OS and it was fine for about another hour, but then it started again. I'm pretty sure it happened after switching back and forth between browse and performance modes. I would practice in performance mode with my normal rigs for a while, then play around with the delays for a bit in browse mode with random rigs. When I went back to practicing in performance mode, I noticed things were off.
I only played around for about 10 min. after the roll back to release OS and restoring my back up. I made sure to change rig presets, switch between modes, switch delays, and all seems well. I'll run through it for a couple hours tomorrow during practice to make sure there isn't something else going on.
PS I loved the new delays while I was playing around though.