Regarding front loading vs rear loading speakers in cabs, I am no expert, but have done this experiment with every cab i've owned and have personally observed:
1) a great sounding guitar cab sounds best with speakers rear loaded. The cab imparts more of its character to the sound.
2) front loading speakers results in less cab color, more true speaker tone
As such, I've front loaded my FRFR 2x12 cab for this reason and would suspect this will achieve a less colored speaker response. FWIW.