I’m no expert but thus far have been using it to mention a song the profile might be good for or what guitar I was using if the profile sounds good. I don't do it for all profiles though and I do with I could also label which pack the profile came from.
In my most extreme comment example it might be:
“[Song Name], Strat, position 4, vol 8, tone 6”
Usually for these I’ll also duplicate the profile as I’m likely tweaking it a little and then moving the duplicated profile into my Original Song folder or Cover song folder.
My most basic comment may be “solo” or “bright”.