Symtoms like headachas could have various root causes and are not always the "same issue". Loosing sound could have many different reasons e.g. a loose contact in a cable ....
patvalley The situation you are describing is intended while Tuner Mode is activated and "Mute Signal" is activated. If you leave Tuner Mode the sound returns. The situation is also normal, if your Mission EP1 is in heel position and controls Volume Pedal. If you are sharing your EP1 for wah and volume ("WahPedal to Volume" ) I guess there is a risk to loose oversight, what is causing drop of volume. If you for example disable a wah effect while the pedal rests in heel position, the pedal transforms into a volume pedal and the slightest move could turn pedal volume down. This again is intended behavior. You can check the current level of volume pedal on page Pedal Links in System Settings.
I've not seen any indication provided by ofirlidor that Tuner Mode nor an expression pedal are involved in his case.
We are not aware of any related software anomaly in current OS versions.