Personally, I prefer the sound of studio profiles than their "merged brothers" through my 2x12 Marshall 1922 cab. I use mostly Top Jimi, Reampzone and Michael Wagener profiles (also tried other popular commercial profiles but didn't like them) and I'm after Mid-High gain Marshall and Boogie sounds. I don't care if a profile is studio or merged, only what sounds best to my ears, and at least for now, the studio ones seem to get the job done for me.