I have found that increasing sensitivity levels often gives me a more sonically desirable increase in gain structure than working with the actual gain control. I like the fact that midrange structure seems to be better retained this way, especially with vintage amp profiles. Finer gain adjustments seem easier as well. I've found this more satisfactory to my taste than using boosts in the stomp section and I like my simple, stomp free, KRemote and Mission expression pedal setup. The input sense doesn't seem to color anything at all and feels much more organic... I'd love to be able to morph the settings.
Or is it all in my head? Sometimes the voices drown things out...