Hi all,
KPA OS: 4.22.12590
RM: 1.6.39
iMac running OSX 10.10.5
RM can see and operate the KPA, and detects that an update to the KPA firmware is needed.
The dowload begins and install, then it fails with a 'Software Update Failed' message.
An error occurred while updating Profiler. Please try again or contact [email protected] for assistance.
I tried again:
Rebooted everything - failed.
Switched out the USB lead connecting the KPA to the iMac - failed
Restarted RM - failed
Started typing in this post
Restarted RM one more time - and it worked!
So, if at first you don't succeed, try, try again 
Note: I learned this approach with KPA/Mac through seeing earlier updates via USB stick failing and causing me to try other sticks, re-downloading etc when all I needed to do was take the damned thing out and put it back in again! (Worked most of the time!) 