I managed to get this working in VirtualBox today. Apologies for any egg sucking here
Firstly, it wouldn't work for me when I first tried, turned out the version I had was horribly out of date (I've not has to use Windoze at home for a very long time) - Make sure you're on the latest version of VirtualBox (4.3.6)
With the Virtual machine loaded, plug the USB-B connector in the back of the Kemper, then plug into the Mac, when you've done that, click the little USB icon in the VirtualBox window (surrounding the windows VM) and click on Kemper Profiler - This will give the VM control of the device and should then install the drivers.
Once that's done, under System / Devices, you should now see 'Profiler'
Again, apologies if the above sounds basic, it's just what I did tonight to get this working.