I go for the Compressor + Pure Boost over the Tube Screamer.
Or Compressor + Treble Boost.
Tube Screamers are mid "honky", IMO, they colour the sound way too much, good for playing live, but not so good at home.
My favourite Overdrive pedal in the KPA would be the combination of the Compressor and Pure Boost.
Compressor intensity between 3.5 and 4.5
Volume +1
Pure Boost Volume at between +0.4 and +1.0