I don't agree 100%
you're dead on about the fact that of course I dial in an amp/micing etc to my liking when profiling it, sure!
So yeah, there's a lot of personal taste and preference involved in that process.
I do not agree about different guitars and players, I'm using all my profiles in the Studio with various diffrent guitars, tunings and players, so they're not tailor made for my specific style and guitars (for my taste? yes, very likely).
This one I've actually played with a Fender USA Strat with Neck Single coil in standard tuning...but I've also used it for another player with a Les Paul with the middle position tuned 2 semitones down.
A good profile IMO works with different players and guitars, but it is of course not universal for all styles and settings.
This profile for example is not dialed in to have the warmest and fullest clean tone for camp fire chord playing etc, it's actually rather scooped and works great for surf guitar sounds with a strat as well as for single note lines with the in-between-settings on a strat and for arpeggiated chord picking on a Les Paul...
I wouldn't use it to record a singer/songwriter ballad of course....but that's not because the player/guitar matters much, it's because different settings/styles demand different sounds...and this one won't work for singer songwriter ballads very well...just like a warm singer/songwriter profile won't work well for Knopfler type of stuff...
But I don't think that's a big surprise to be honest, is it?
I's always about picking the right tools for the job, and a profile is just that, a tool...if your jigsaw doesn't do a good job putting a nail into the wall, it's not the jigsaw's fault...it's just not the right tool.
I do have a couple of those thick warm sounding clean profile as well (Fender Combo, Jackson Reference 100 (!!!) etc.....but I can't give you all my tools, can I? )