Are they the same profiles tweaked differently?
Yes - I would say so - you can go back and forth between the similarly named patches in the two folders and the Eq settings on the front panel of the KPA do not change but the brightness etc of the patch does. These have been dialed in for the respective pickup styles SC vs HB.
So for example, the third patch in each list - 2Rock Clean, definition is 7.0 for the HB and 6.1 for the tele.
As far as the sound of these with humbuckers I am seriously impressed - the sound of these with a 335 or an LP is just superb. Classic rock tones of every stripe. Andy is not kidding about his new setup.