Even some humbuckers can get noisy with neon and fluorescent lights. You're more likely to run into fluorescent fixtures and not even know it.
One location at my church had fluorescent lights in the room. My single coil telecaster *hated* that room. I would ride the volume knob or pedal and still get so much noise I wanted to scream.
I switched pickups not specifically because of the noise (though that was part of it). I went to a set of Fishman Fluence pups, which are active and as quiet as a tomb regardless of what's floating around.
Also....make sure your phone or other device isn't in close proximity. Not even active pickups can ignore that crap.