i dont use OD pedals much (get all my drive from the amps themselves) so I haven’t tested it properly but I think clean sens will affect the level with OD pedals in a similar way to amps. It is easy to test though. When you engage an OD with a lot of drive does the sound get quieter? If so try lowering clean sens and test again.
If you want to hear what a wrong setting sounds like for comparison, use a clean tig, set clean sens high, now increase the gain on the profile gradually. You should notice that the perceived volume actually drops. Now set clean sense really low and do the same thing. You should find that increasing gain makes the perceived level louder.