while i am @ 98% with joe b., i am total failure when it comes to carlos ... no matter which profile i use.
First of all you need the guitar with the best sustain that you can possibly find.
Then get Armin's profile pack 28 (Mesa Boogie MKV), don't forget to add some boost as soon as you picked the profile that fits Carlos' tone and your guitar best.
Armin's Mesa Boogies are a brilliant example of his profiles' strength. You get lots of choice and then you can build great results on top of that wonderful basis.
Don't forget to EQ, Carlos doesn't like bright and shiny tone, he's more on the dark side, but still some nice gloss. It's easy to find yourself under a blanket after tweaking a while, try to avoid that.