For me it depends on the purpose. For Live I always use an EQ-Preset based on TJ. For me most of the profiles lack appropriate mids. They sound awesome on their own but hard to hear at rehearsal.
I do not think that one should feel guilty by tweaking. The main issue is that one does not have the same guitar used dialing in the tone and second one does not have the same speakers being used to monitor the tone. So hard to achieve the same results anyway.
I agree, getting the good midrange for live with the kemper is rather difficult...
What EQ preset are you applying? Would help me a lot.
Thanxs